How Precise Are New Genomic Techniques?
Many claims of precision and predictability of gene editing technology are not supported by experimental evidence, according to Professor emeritus Michael Antoniou.
In our latest NRP 84 webinar, Professor emeritus Michael Antoniou from King’s College London examined the scientific uncertainties surrounding new genomic techniques (NGTs) and their use in agriculture. While acknowledging the potential benefits of modern biotechnology, he questioned whether gene editing is as precise, predictable and safe as sometimes claimed.
A central focus of the presentation was the use of CRISPR Cas technology in plant breeding. Antoniou explained that although gene editing can introduce targeted changes into plant DNA, the process can also produce unintended modifications. These may include changes at unintended locations in the genome, larger DNA rearrangements and the accidental integration of foreign DNA. According to Antoniou, such effects demonstrate why both the gene editing process and its final products should be considered in safety assessments.
The webinar also addressed the upcoming European regulatory framework for NGTs. Antoniou expressed concern about the idea of exempting certain gene-edited plants from the safety assesment and labelling requirements applied to genetically modified organisms. He advocated for more comprehensive molecular analyses, including genome sequencing and biochemical profiling, to identify possible unintended effects on plant composition, nutritional value and food safety.
NRP 84 webinar recordings are available on request.